Jasinski Hits 500

Professor Jerry Jasinski (Chemistry) has reached a major milestone in his long academic career at Keene State. In collaboration with his many regional, national and international colleagues, he has now co-authored over 500 research papers in major refereed scientific journals related to his work focused on the X-ray crystallography and structure of biologically and pharmaceutically significant molecules.

In conjunction with the recent acquisition of a new state-of-the-art CCD single crystal X-ray diffractometer system from a National Science Foundation grant, he has extended his research activities to directly include KSC undergraduate students as well as faculty and students from several New England Colleges (Dartmouth, Middlebury, Williams, St. Anselm’s, Clark, UMASS-Boston, UMSS-Dartmouth, Fairfield, University of New Hampshire), regionally (Howard and Catholic Universities) and with significant collaborations globally. These include faculty and students from India (Universities of Mysore, Mangalore, IIT-Deli, IIT-Bombay, Guru Nanak Dev, JIWAJI- Gwailor, Manipur, Punjab-Chandigarh), Iran (Mashhad), Pakistan (Allama Iqbql Open University), Senegal (Faculate des Sciences et Techniques), South Africa (Nelson Mandela Metropolitan University), Turkey (Earciyes) and the West Indies (Cave Hill). His Fulbright-Nehru scholarship to India during the fall, 2013 semester significantly increased his international exposure and productivity.

In this venue, KSC undergraduates become directly involved as collaborators and enhance their professional exposure by allowing them to share data, computational tools and ideas related to projects of synthetic, biological and pharmaceutical interest. They advance their communication skills by becoming directly involved in these projects from a crystallography and structural perspective under the mentorship of Professor Jasinski and become co-authors on major research papers. These opportunities have in the past and continue to pave the way toward selective entrance into quality graduate schools or positions in science related industry or as science teachers in a most competitive world. Over the past 30 years KSC undergraduates have coauthored over 160 of these papers. Over the past five years Professor Jasinski has co-authored between 40-60 papers a year, a phenomenal pace at any institution.

Listed below are examples of the work put forth by Jasinski and his research students in the past year or so (asterisks indicate KSC student co-authors):

“Two tautomers in the same crystal: 3-(4-fluorophenyl)-1H-pyrazole and 5-(4-fluorophenyl)-1H-pyrazole,” Thammarse S. Yamuna, Manpreet Kaur, Jerry P. Jasinski, Brian J. Anderson, H. S. Yathirajan, Acta Crystallographica Section E: Structure Reports (2014) 70 (8), o949-o950.

“N-Ethyl-2-[1-(2-hydroxy-4-methylphenyl) ethylidene] hydrazinecarbothioamide,” BJ Anderson, JR Hall*, JP Jasinski Acta Crystallographica Section E: Structure Reports Online (2014) 70 (6), o735-o735.

“N-Ethyl-2-[1-(2-hydroxynaphthalen-1-yl) ethylidene] hydrazinecarbothioamide,” BJ Anderson, ZA Shalit*, JP Jasinski Acta Crystallographica Section E: Structure Reports Online (2014) 70 (6), o732-o732.

“New polyfunctional imidazo [4, 5-C] pyridine motifs: Synthesis, crystal studies, docking studies and antimicrobial evaluation,” G Jose, TH Suresha Kumara, G Nagendrappa, HBV Sowmya, JP Jasinski, SP Millikan*, European Journal of Medicinal Chemistry (2014) 77, 288-297.

“Synthesis, spectroscopy, fluorescence and crystal structures of cyclopalladated dinuclear complexes with C, N-chelating azobenzenes and N, S-bridging heterocyclic-2-thiolates,” TS Lobana, AK Sandhu, A Kaur, JP Jasinski Journal of Organometallic Chemistry (2014) 751, 519-524.

“Synthesis, characterization, and computational study of three-coordinate SNS-copper (I) complexes based on bis-thione precursors,” JR Miecznikowski, MA Lynn, JP Jasinski, E Reinheimer, DW Bak, M Pati, Journal of Coordination Chemistry (2014) 67 (1), 29-44.

“{2-[1-(2-Methoxy-6-oxidophenyl-O6) ethylidene]-N methylhydrazinecarbothioamidato-2N2, S}(triphenylphosphane-P) palladium (II) ethanol monosolvate,” BJ Anderson, KA O’Rourke, AM Keeler, JP Jasinski Acta Crystallographica Section E: Structure Reports Online (2013) 69 (10), m528-m529.

“Ethyl 2-amino-6-(4-bromophenyl)-4-(4-fluorophenyl) cyclohexa-1, 3-diene-1-carboxylate,” B Narayana, M Sapnakumari, JP Jasinski, PM Fraiser*, HS Yathirajan Acta Crystallographica Section E: Structure Reports Online (2013) 69 (9), o1473-o1473.

“3-Amino-1H-pyrazol-2-ium trifluoroacetate,” TS Yamuna, JP Jasinski, DR Scadova*, HS Yathirajan, M Kaur Acta Crystallographica Section E: Structure Reports Online (2013) 69 (9), o1425-o1426.

“Synthesis and Crystal Structures of Four New Dihydropyridine Derivatives,” JP Jasinski, CJ Guild, AE Pek, S Samshuddin, B Narayana, HS Yathirajan, (2013) _Journal of Chemical Crystallography _43 (8), 429-442.

“Bruceolline J: 2-hydroxy-3, 3-dimethyl-2, 3-dihydrocyclopenta [b] indol-1 (4H)-one,” JM Lopchuk, GW Gribble, SP Millikan*, JP Jasinski Acta Crystallographica Section E: Structure Reports Online (2013) 69 (8), o1351-o1352.

“Flunarizinium hydrogen maleate,” CN Kavitha, JP Jasinski, SM Matar*, HS Yathirajan, AR Ramesha Acta Crystallographica Section E: Structure Reports Online (2013) 69 (8), o1344-o1344.

“2-[1-(2-Hydroxy-4-methoxyphenyl) ethylidene]-N-methylhydrazinecarbothioamide,” BJ Anderson, MB Freedman, SP Millikan, JP Jasinski Acta Crystallographica Section E: Structure Reports Online (2013) 69 (8), o1315-o1315.

“Carbinoxaminium dipicrate,” V Ramya, JP Jasinski, JP Shannon*, HS Yathirajan, DK Ravishankara Acta Crystallographica Section E: Structure Reports Online (2013) 69 (8), o1264-o1265.

“2-[(2-Chlorophenyl)(hydroxy) methyl] phenol,” G Prakasha, JP Jasinski, JS Brown*, HS Yathirajan, DK Ravishankara Acta Crystallographica Section E: Structure Reports Online (2013) 69 (8), o1240-o1240.