The American Studies program offers students an interdisciplinary liberal arts education. Students in American Studies engage in a challenging exploration of historical and contemporary American culture and the American multicultural identity, including its past and present values, conflicts, and experiences.

The Bachelor of Science in Applied Computer Science provides students with a thorough grounding in computer programming and information science and an introduction to the various branches of computer science. The primary focus is to prepare students to successfully operate as information science (IS) or information technology (IT) professionals, and/or pursue graduate studies in CS or a related field.

The Architecture major at Keene State College is a preprofessional four-year program designed to give students a solid foundation in the artistic, scientific, and technical aspects of architecture. The curriculum offers a range of courses in studio design, building science, sustainable design, history/theory, digital technology, and practice.

The Bachelor of Arts degree in Art is designed to meet a variety of student needs through courses in art history, painting, sculpture, printmaking, ceramics, drawing, photography, and graphic design. Through the program's flexibility and rich variety, students are encouraged to develop their skills and broaden their knowledge in courses that can lead to graduate school or a variety of careers in visual art and graphic design. Options in Studio Art and Graphic Design are available

The Bachelor of Art (B.F.A.) degree program is designed to provide students with an intensely comprehensive course of study consisting of a minimum of 72 credits in visual arts courses. The B.F.A. degree can lead directly to graduate study (M.F.A.) or to professional careers in the Graphic Design field. To be eligible for the B.F.A. degree, students must first be accepted into the B.A. program in Art.

Keene State College offers a CAATE (Commission on Accreditation of Athletic Training Education) accredited undergraduate Athletic Training education program designed for those students who wish to pursue certification as an athletic trainer.

The Bachelor of Arts in Biology (B.A.) provides an introduction to the discipline and an opportunity to integrate the study of Biology with another field. In contrast to the B.S. program, the B.A. requires fewer credits in both biology and related sciences, permitting a student to complete a second major or additional courses in another discipline such as Chemistry, Psychology, Elementary Education, Journalism, Art, Management, or Computer Science; thus, it satisfies the needs of students with a combination of interests.

The Bachelor of Science program in Biology (B.S) is designed to stimulate intellectual and personal growth through an examination of the fundamental properties of living systems, the application of experimental and descriptive methods of discovery, and the consideration of the social, ethical, and aesthetic aspects of biological knowledge. The B.S. program also provides undergraduate preparation for technical employment or post-baccalaureate study in graduate school or for professions such as medicine, dentistry, veterinary medicine, teaching, and natural resource management. A Biology major considering graduate or professional school should confer with a Biology advisor to plan a program to meet the student's specific needs and assure entrance into such a school.

Broadly based in the liberal arts tradition, the B.A. in Chemistry (B.A.) has been designed for students interested in careers in areas that use chemistry as a base, such as the health-related professions, pharmaceutical marketing, secondary science education, chemistry-related industry, and/or entrance to graduate school.

The B.S. in Chemistry (B.S.) should serve as a general preparation for a professional scientist. The major was designed according to guidelines from the American Chemical Society (ACS) to be rigorous, yet flexible enough to allow for preparation for immediate employment, graduate study, or work in an allied profession.

Chemistry-Physics: in today's changing job market, competency in two or more basic fields of science enhances opportunity for employment and professional growth potential. This major fulfills such a need. This interdisciplinary major provides grounding in two related sciences, with balance in both.

The Communication major is an interdisciplinary program combining courses in Communication, Journalism, and Philosophy. The major is designed to take a broad-based, humanities-centered view of the symbolic ways humans create meaning. The program will focus on the development of skills as students learn to work with various communication tools to improve their own ability to interact effectively with others. Students will also increase their critical awareness as they study the structure, patterns, and effects of communication on both themselves and society.

Computer Mathematics: this program provides students with a thorough grounding in both computer science (CS) and mathematics. This nexus between CS and mathematics is both historical and logical; the program capitalizes on this association to provide students with the best opportunity to pursue careers in either field.

The B.A. in Economics combines rigorous training in economic theory with application to contemporary issues such as globalization, financial market volatility, and the environment. The Economics program is a tight-knit community, and majors and minors can expect to work closely with faculty and with each other.

The Education major has four tracks:
Early Childhood Development
Elementary Education
Secondary Education
Elementary and Special Education
Additionally, students in two specialized programs that lead to K-12 certification – Physical Education Teacher Certification and Music Education – take courses offered in the program.

The Engineering, B.S. (transfer program) prepares students to transfer to engineering schools after completing integrative studies requirements and foundation courses in mathematics, physics, chemistry, and computer science at Keene State College.

Students in the English, B.A. program will study the historical development of literary and rhetorical traditions, of literatures written in English, as well as world and European literatures in English translation.

The Environmental Studies, B.S. (ENST) Program provides students with a conceptual framework and set of skills needed to make effective, relevant, and sustaining contributions to society with respect to environmental issues, both as professional practitioners and as individual citizens.

The Film Studies major balances theoretical and applied course work. Options offer opportunities to prepare for employment in a variety of fields; graduates most often go on to further study or careers in the analysis and/or production of film and television or to careers in areas of the business world such as personnel, counseling, advertising, public relations, and sales.

The French allows students to acquire an active command of written and spoken French, with a knowledge of historical and contemporary issues in the French-speaking world.

The B.A. in General Science provides a broad-based foundation in three major areas: Earth/Space Science, Life Science, and Physical Science. This major would provide general science knowledge for working in science museums, zoos, science camps, or state or national parks.

Geography is an empowering discipline that examines the Earth through the lens of human-environment interaction. Major topics of study include population distributions, climate change, technology, language, urbanization, globalization, resource management, and environmental impacts.

Geology is the study of the Earth and its environs. It involves detailed consideration of planet Earth's interior and its surface, as well as consideration of the hydrosphere, atmosphere, and setting in space.

Health Science is an interdisciplinary program comprised of courses in Health Promotion and Health Fitness, Nutrition, Substance Abuse and Addictions, Biology, Chemistry, Management, and Exercise Science.

As a field of study, History provides students with many of the necessary skills for a productive professional career and an intellectually fulfilling life. Toward these ends, the History major attempts to provide students with the ability to think and read critically and analytically, to form sound opinions and support them with logical arguments based on documentary evidence, to communicate ideas effectively, and to conduct historical research.

In the Holocaust and Genocide Studies program students examine both the Holocaust and the broader topic of genocide. The graduate in Holocaust and Genocide Studies is prepared to support curriculum development in the social studies and history and to pursue careers in social and governmental service.

An Individualized Major is composed of an interdisciplinary program of studies, appropriately designed (1) to enhance the student's ability to integrate and synthesize content and/or method from two or more academic disciplines and (2) to satisfy an individual student's educational interests or career objectives.

The Journalism major at Keene State College provides and maintains an intellectual environment dedicated to the investigation of the roles of the mass media in contemporary society within a liberal arts perspective.

The Management major is a career-oriented program, emphasizing management skills and building on a solid foundation in the liberal arts and sciences, is designed to prepare individuals for management careers in industrial or public organizations and for graduate work.

The Bachelor of Arts in Mathematics provides students breadth and depth through an integrated approach to the study of mathematics. The program prepares students for either an immediate career, especially teaching, or graduate school.

The Mathematics Education for Elementary Teachers program is designed to prepare candidates for grades K-8 elementary school teaching with a specialization in mathematics.

The interdisciplinary program in Mathematics-Physics provides sufficient groundwork in both mathematics and physics for employment in industry, the commercial sector, or further study in graduate school.

The Music Education curriculum prepares teachers and supervisors of music for kindergarten through grade 12.

Upon successful completion of an audition into the Music Performance program, students declare a primary instrument or voice; 32 credits of Applied Music must then be taken in the primary instrument or voice.

The Music provides a broad foundation in music and is also appropriate for students planning on graduate study. Five specializations are available:
Composition
Music History
Music for Elementary Teachers
Music Technology
Music Theory

This interdisciplinary program is designed to prepare students to teach Physical Education in public schools and meets all current requirements by the State of New Hampshire for certification in physical education for grades K to 12.

The Political Science major provides students with an understanding of politics and government as practiced in the United States and throughout the world, a knowledge of global political relationships, opportunities to develop skills that are useful both in the course of participating first-hand in politics and in the rigorous analysis and communication of complex information, familiarity with methods used in the study of political science, and preparation for professional careers in law, government, international affairs, and the teaching of politics and the social sciences.

The Psychology
program prepares students for success in a graduate program in psychology and/or a career in a psychology related field. The program exposes students to the methodologies, problems, bodies of knowledge, and broad range of perspectives found currently in psychology.

The Safety Studies major prepares students for a variety of occupational safety and health program management positions in the private and public sector.

The Social Science program provides a broad overview of several liberal arts and sciences. Among other purposes, it is useful as pre-law preparation and graduate work in the policy studies areas.

The Sociology program offers students knowledge and resources to search systematically for answers to questions about society.

The Spanish major allows students to acquire an active command of written and spoken Spanish, with a knowledge of historical and contemporary issues in the Spanish-speaking world.

The Sustainable Product Design and Innovation major at Keene State College is a pre-professional four-year program offering a cross-disciplinary curriculum to give the student a solid foundation in the artistic, scientific, and technical aspects of product design and the social and scientific aspects of sustainability concerns.

The Department of Theatre and Dance is dedicated to providing a comprehensive course of study that balances theory and practice within a sound liberal arts education.